CPRiL

FKBP3

FKBP prolyl isomerase 3

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]

• peptidyl-prolyl cis-trans isomerase FKBP3
• 25 kDa FK506-binding protein
• 25 kDa FKBP
FK506 binding protein 3, 25kDa
FK506-binding protein 25, T-cell
FK506-binding protein 3
PPIase FKBP3
immunophilin FKBP25
rapamycin binding protein
rapamycin-selective 25 kDa immunophilin
rotamase
FKBP-25
FKBP-3
FKBP25
PPIase