Protein Name bone morphogenetic protein receptor, type 1B
Organism Mus musculus
Gene ID 12167
Gene Symbol

Bmpr1b

UniProt P36898 (BMR1B_MOUSE), B2RRZ4 (B2RRZ4_MOUSE), Q3USS1 (Q3USS1_MOUSE)
Relationships Total Number of functionally related compound(s) : 13
Total Number of Articles : 13
Description

bone morphogenetic protein receptor, type 1B

Gene Summary

This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important in skeletal and bone development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

synonyms
  • bone morphogenetic protein receptor type-1B
  • BMP type-1B receptor
  • activin receptor-like kinase 6
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Properties