CPRiL

Uhrf1

ubiquitin-like, containing PHD and RING finger domains, 1

Enables several functions, including hemi-methylated DNA-binding activity; histone H3K9me2/3 reader activity; and histone binding activity. Involved in negative regulation of gene expression via chromosomal CpG island methylation and negative regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear matrix; and replication fork. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hindlimb phalanx; and sensory organ. Orthologous to human UHRF1 (ubiquitin like with PHD and ring finger domains 1). [provided by Alliance of Genome Resources, Jul 2025]

• E3 ubiquitin-protein ligase UHRF1
• RING-type E3 ubiquitin transferase UHRF1
• mUhrf1
nuclear protein 95
nuclear zinc finger protein Np95
ubiquitin-like PHD and RING finger domain-containing protein 1
ubiquitin-like-containing PHD and RING finger domains protein 1
ICBP90
Np95
RNF106