Protein Name C-C motif chemokine ligand 7
Organism Mus musculus
Gene ID 20306
Gene Symbol

Ccl7

UniProt Q03366 (CCL7_MOUSE), A9Z1Z1 (A9Z1Z1_MOUSE)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 37
Description

C-C motif chemokine ligand 7

Gene Summary

Enables CCR2 chemokine receptor binding activity. Predicted to be involved in several processes, including cellular response to ethanol; eosinophil chemotaxis; and positive regulation of natural killer cell chemotaxis. Predicted to act upstream of or within canonical NF-kappaB signal transduction; positive regulation of inflammatory response; and regulation of gene expression. Located in extracellular space. Is expressed in several structures, including central nervous system; leg; lung; retina; and vertebral axis musculature. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • C-C motif chemokine 7
  • RANTES/sis homolog
  • chemokine (C-C motif) ligand 7
Click to show/hide the synonyms
Properties