Protein Name | C-C motif chemokine ligand 7 |
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Organism | Mus musculus |
Gene ID | 20306 |
Gene Symbol | Ccl7 |
UniProt | Q03366 (CCL7_MOUSE), A9Z1Z1 (A9Z1Z1_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
43
Total Number of Articles : 37 |
Description |
C-C motif chemokine ligand 7 |
Gene Summary |
Enables CCR2 chemokine receptor binding activity. Predicted to be involved in several processes, including cellular response to ethanol; eosinophil chemotaxis; and positive regulation of natural killer cell chemotaxis. Predicted to act upstream of or within canonical NF-kappaB signal transduction; positive regulation of inflammatory response; and regulation of gene expression. Located in extracellular space. Is expressed in several structures, including central nervous system; leg; lung; retina; and vertebral axis musculature. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). [provided by Alliance of Genome Resources, Jun 2025] |
synonyms |
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Properties | |