Protein Name sterile alpha and HEAT/Armadillo motif containing 1
Organism Mus musculus
Gene ID 237868
Gene Symbol

Sarm1

UniProt Q6PDS3 (SARM1_MOUSE)
Relationships Total Number of functionally related compound(s) : 38
Total Number of Articles : 37
Description

sterile alpha and HEAT/Armadillo motif containing 1

Gene Summary

Enables NAD+ nucleosidase activity. Involved in several processes, including NAD+ catabolic process; regulation of dendrite morphogenesis; and regulation of synapse pruning. Acts upstream of or within regulation of neuron apoptotic process and response to glucose. Located in several cellular components, including dendrite; microtubule; and mitochondrial outer membrane. Part of protein-containing complex. Is active in cell surface and neuromuscular junction. Is expressed in immune system; nervous system; neural retina; and tongue. Orthologous to human SARM1 (sterile alpha and TIR motif containing 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • NAD(+) hydrolase SARM1
  • NADP(+) hydrolase SARM1
  • NADase SARM1
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Properties