Protein Name acyl-CoA wax alcohol acyltransferase 1
Organism Homo sapiens
Gene ID 158833
Gene Symbol

AWAT1

UniProt Q58HT5 (AWAT1_HUMAN)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 28
Description

acyl-CoA wax alcohol acyltransferase 1

Gene Summary

The protein encoded by this gene belongs to the diacylglycerol acyltransferase family. It esterifies long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that this enzyme plays a central role in lipid metabolism in skin. Consistent with this observation, this protein is predominantly expressed in the sebaceous gland of the skin. [provided by RefSeq, Sep 2009]

synonyms
  • acyl-CoA wax alcohol acyltransferase 1
  • diacyl-glycerol acyltransferase 2
  • diacylglycerol O-acyltransferase 2-like 3
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Properties