Protein Name Sp7 transcription factor
Organism Rattus norvegicus
Gene ID 300260
Gene Symbol

Sp7

UniProt Q6IMK2 (Q6IMK2_RAT), Q6IMK1 (Q6IMK1_RAT)
Relationships Total Number of functionally related compound(s) : 65
Total Number of Articles : 65
Description

Sp7 transcription factor

Gene Summary

Predicted to enable DEAD/H-box RNA helicase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to parathyroid hormone stimulus; cellular response to zinc ion starvation; and response to insulin. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • transcription factor Sp7
  • osterix
  • Osx
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Properties