Protein Name calcium/calmodulin-dependent protein kinase IV
Organism Mus musculus
Gene ID 12326
Gene Symbol

Camk4

UniProt Q8BGR3 (Q8BGR3_MOUSE)
Relationships Total Number of functionally related compound(s) : 53
Total Number of Articles : 72
Description

calcium/calmodulin-dependent protein kinase IV

Gene Summary

Predicted to enable calcium-dependent protein serine/threonine kinase activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Involved in postsynapse to nucleus signaling pathway and postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within several processes, including neuron-neuron synaptic transmission; positive regulation of DNA-templated transcription; and positive regulation of protein export from nucleus. Located in cytoplasm and nucleus. Is active in GABA-ergic synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human CAMK4 (calcium/calmodulin dependent protein kinase IV). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • calcium/calmodulin-dependent protein kinase type IV
  • CAM kinase-GR
  • Ca2+/calmodulin-dependent protein kinase type IV/Gr
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Properties