Protein Name N-ribosyldihydronicotinamide:quinone dehydrogenase 2
Organism Homo sapiens
Gene ID 4835
Gene Symbol

NQO2

UniProt P16083 (NQO2_HUMAN), Q5TD07 (Q5TD07_HUMAN), B3KPX6 (B3KPX6_HUMAN)
Relationships Total Number of functionally related compound(s) : 199
Total Number of Articles : 137
Description

N-ribosyldihydronicotinamide:quinone dehydrogenase 2

Gene Summary

This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

synonyms
  • ribosyldihydronicotinamide dehydrogenase [quinone]
  • N-ribosyldihydronicotinamide:quinone reductase 2
  • NAD(P)H dehydrogenase, quinone 2
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Properties