| Protein Name | presenilin enhancer gamma secretase subunit |
|---|---|
| Organism | Mus musculus |
| Gene ID | 66340 |
| Gene Symbol | Psenen |
| UniProt | Q9CQR7 (PEN2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
38
Total Number of Articles : 38 |
Description |
presenilin enhancer gamma secretase subunit |
| Gene Summary |
Enables endopeptidase activator activity. Involved in positive regulation of endopeptidase activity and protein processing. Acts upstream of or within Notch receptor processing. Part of gamma-secretase complex. Is expressed in early tubule; female associated reproductive structure; male associated reproductive structure; ovary; and testis. Human ortholog(s) of this gene implicated in hidradenitis suppurativa. Orthologous to human PSENEN (presenilin enhancer, gamma-secretase subunit). [provided by Alliance of Genome Resources, Jun 2025] |
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