| Protein Name | cullin 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 26554 |
| Gene Symbol | Cul3 |
| UniProt | Q9JLV5 (CUL3_MOUSE), Q9CTE0 (Q9CTE0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
21
Total Number of Articles : 23 |
Description |
cullin 3 |
| Gene Summary |
Enables cyclin binding activity and identical protein binding activity. Involved in several processes, including embryonic cleavage; integrin-mediated signaling pathway; and regulation protein catabolic process at postsynapse. Acts upstream of or within with a positive effect on protein polyubiquitination. Acts upstream of or within several processes, including embryonic morphogenesis; fibroblast apoptotic process; and liver morphogenesis. Located in Golgi apparatus and nucleus. Is active in glutamatergic synapse. Is expressed in several structures, including cerebral cortex; extraembryonic component; gonad; hemolymphoid system gland; and liver. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Orthologous to human CUL3 (cullin 3). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |