| Protein Name | SMAD family member 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 17125 |
| Gene Symbol | Smad1 |
| UniProt | P70340 (SMAD1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
133
Total Number of Articles : 152 |
Description |
SMAD family member 1 |
| Gene Summary |
Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and primary miRNA binding activity. Involved in several processes, including cell surface receptor protein serine/threonine kinase signaling pathway; osteoblast differentiation; and positive regulation of miRNA transcription. Acts upstream of or within several processes, including brain development; positive regulation of macromolecule biosynthetic process; and skeletal system development. Located in cytoplasm and nucleus. Part of homomeric SMAD protein complex and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human SMAD1 (SMAD family member 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |