| Protein Name | BTB and CNC homology, basic leucine zipper transcription factor 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12014 |
| Gene Symbol | Bach2 |
| UniProt | P97303 (BACH2_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 11 |
Description |
BTB and CNC homology, basic leucine zipper transcription factor 2 |
| Gene Summary |
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in import into nucleus and negative regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including ganglia; limb bud; reproductive system; telencephalon; and urinary system. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |