Protein Name protein arginine N-methyltransferase 5
Organism Mus musculus
Gene ID 27374
Gene Symbol

Prmt5

UniProt Q8CIG8 (ANM5_MOUSE), A0A0R4J049 (A0A0R4J049_MOUSE)
Relationships Total Number of functionally related compound(s) : 34
Total Number of Articles : 50
Description

protein arginine N-methyltransferase 5

Gene Summary

This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation and the assembly of small nuclear ribonucleoproteins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

synonyms
  • protein arginine N-methyltransferase 5
  • Jak-binding protein 1
  • SKB1 homolog
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Properties