| Protein Name | dynamin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1759 |
| Gene Symbol | DNM1 |
| UniProt | Q05193 (DYN1_HUMAN), B4DK06 (B4DK06_HUMAN), B7ZAC0 (B7ZAC0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
58
Total Number of Articles : 60 |
Description |
dynamin 1 |
| Gene Summary |
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
| synonyms |
|
| Properties | |