| Protein Name | HDGF like 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 84717 |
| Gene Symbol | HDGFL2 |
| UniProt | Q7Z4V5 (HDGR2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
18
Total Number of Articles : 17 |
Description |
HDGF like 2 |
| Gene Summary |
This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
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| Properties | |