| Protein Name | TIMP metallopeptidase inhibitor 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29543 |
| Gene Symbol | Timp2 |
| UniProt | P30121 (TIMP2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
127
Total Number of Articles : 139 |
Description |
TIMP metallopeptidase inhibitor 2 |
| Gene Summary |
Enables integrin binding activity and metalloendopeptidase inhibitor activity. Involved in several processes, including negative regulation of proteolysis; positive regulation of adenylate cyclase activity; and regulation of intracellular signal transduction. Located in several cellular components, including cell surface; growth cone; and neuronal cell body. Used to study portal hypertension. Biomarker of cardiomyopathy; congestive heart failure; and intracranial aneurysm. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human TIMP2 (TIMP metallopeptidase inhibitor 2). [provided by Alliance of Genome Resources, Jun 2025] |
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