Protein Name tripartite motif containing 28
Organism Homo sapiens
Gene ID 10155
Gene Symbol

TRIM28

UniProt Q13263 (TIF1B_HUMAN)
Relationships Total Number of functionally related compound(s) : 72
Total Number of Articles : 84
Description

tripartite motif containing 28

Gene Summary

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

synonyms
  • transcription intermediary factor 1-beta
  • E3 SUMO-protein ligase TRIM28
  • KAP-1
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Properties