Protein Name ferritin heavy polypeptide 1
Organism Mus musculus
Gene ID 14319
Gene Symbol

Fth1

UniProt P09528 (FRIH_MOUSE)
Relationships Total Number of functionally related compound(s) : 52
Total Number of Articles : 90
Description

ferritin heavy polypeptide 1

Gene Summary

Enables identical protein binding activity and iron ion binding activity. Acts upstream of or within iron ion transport. Located in mitochondrion. Is active in cytosol and membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hemochromatosis type 5 and neurodegeneration with brain iron accumulation. Orthologous to human FTH1 (ferritin heavy chain 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • ferritin heavy chain
  • H-ferritin
  • ferritin H subunit
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Properties