| Protein Name | renin 1 structural |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19701 |
| Gene Symbol | Ren1 |
| UniProt | P06281 (RENI1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
55
Total Number of Articles : 43 |
Description |
renin 1 structural |
| Gene Summary |
Enables aspartic-type endopeptidase activity. Involved in angiotensin maturation; male gonad development; and mesonephros development. Acts upstream of or within with a positive effect on regulation of blood pressure. Acts upstream of or within several processes, including drinking behavior; hormone-mediated signaling pathway; and renin-angiotensin regulation of aldosterone production. Located in extracellular space. Is active in extracellular region. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant tubulointerstitial kidney disease 4; essential hypertension; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |