Protein Name sirtuin 6
Organism Rattus norvegicus
Gene ID 299638
Gene Symbol

Sirt6

UniProt Q4FZY2 (Q4FZY2_RAT)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 35
Description

sirtuin 6

Gene Summary

Enables protein lysine deacetylase activity. Involved in several processes, including cellular response to hydrogen peroxide; cellular response to peptide hormone stimulus; and post-embryonic cardiac muscle cell growth involved in heart morphogenesis. Predicted to be located in chromosome, subtelomeric region and nucleoplasm. Predicted to be active in chromosome; endoplasmic reticulum; and nucleus. Biomarker of metabolic dysfunction-associated steatotic liver disease; obesity; and transient cerebral ischemia. Orthologous to human SIRT6 (sirtuin 6). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • NAD-dependent protein deacylase sirtuin-6
  • NAD-dependent deacetylase sirtuin-6
  • NAD-dependent protein deacetylase sirtuin-6
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Properties