Protein Name mitogen activated protein kinase kinase 3
Organism Rattus norvegicus
Gene ID 303200
Gene Symbol

Map2k3

UniProt B1H230 (B1H230_RAT), Q498S1 (Q498S1_RAT)
Relationships Total Number of functionally related compound(s) : 39
Total Number of Articles : 23
Description

mitogen activated protein kinase kinase 3

Gene Summary

Predicted to enable MAP kinase kinase activity and protein kinase binding activity. Involved in several processes, including cellular response to lipopolysaccharide; cellular response to sorbitol; and response to ischemia. Used to study retinal disease. Human ortholog(s) of this gene implicated in cervical cancer and restrictive cardiomyopathy. Orthologous to human MAP2K3 (mitogen-activated protein kinase kinase 3). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • dual specificity mitogen-activated protein kinase kinase 3
  • dual specificity mitogen-activated protein kinase kinase 3-like
  • Mek3
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Properties