Protein Name prospero homeobox 1
Organism Mus musculus
Gene ID 19130
Gene Symbol

Prox1

UniProt P48437 (PROX1_MOUSE)
Relationships Total Number of functionally related compound(s) : 31
Total Number of Articles : 31
Description

prospero homeobox 1

Gene Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including camera-type eye morphogenesis; circulatory system development; and positive regulation of cell differentiation. Acts upstream of or within several processes, including epithelial cell differentiation; hepatocyte cell migration; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; sensory organ; and skin. Used to study dilated cardiomyopathy and obesity. Orthologous to human PROX1 (prospero homeobox 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • prospero homeobox protein 1
  • homeobox prospero-like protein PROX1
  • prospero-related homeobox 1
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Properties