Protein Name nuclear transcription factor Y subunit beta
Organism Homo sapiens
Gene ID 4801
Gene Symbol

NFYB

UniProt P25208 (NFYB_HUMAN), F8VSL3 (F8VSL3_HUMAN), A0A024RBG7 (A0A024RBG7_HUMAN)
Relationships Total Number of functionally related compound(s) : 27
Total Number of Articles : 16
Description

nuclear transcription factor Y subunit beta

Gene Summary

The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]

synonyms
  • nuclear transcription factor Y subunit beta
  • CAAT box DNA-binding protein subunit B
  • CCAAT-binding transcription factor subunit A
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Properties