Protein Name lysine acetyltransferase 2A
Organism Homo sapiens
Gene ID 2648
Gene Symbol

KAT2A

UniProt Q92830 (KAT2A_HUMAN)
Relationships Total Number of functionally related compound(s) : 112
Total Number of Articles : 141
Description

lysine acetyltransferase 2A

Gene Summary

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]

synonyms
  • histone acetyltransferase KAT2A
  • GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2
  • General control of amino acid synthesis, yeast, homolog-like 2
Click to show/hide the synonyms
Properties