Protein Name | lysine acetyltransferase 2A |
---|---|
Organism | Homo sapiens |
Gene ID | 2648 |
Gene Symbol | KAT2A |
UniProt | Q92830 (KAT2A_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
112
Total Number of Articles : 141 |
Description |
lysine acetyltransferase 2A |
Gene Summary |
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009] |
synonyms |
|
Properties | |