Protein Name Fc gamma receptor IIIb
Organism Homo sapiens
Gene ID 2215
Gene Symbol

FCGR3B

UniProt O75015 (FCG3B_HUMAN), A0A087WU90 (A0A087WU90_HUMAN), A0A087WZR4 (A0A087WZR4_HUMAN), A0A3B3ISU3 (A0A3B3ISU3_HUMAN)
Relationships Total Number of functionally related compound(s) : 71
Total Number of Articles : 78
Description

Fc gamma receptor IIIb

Gene Summary

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

synonyms
  • low affinity immunoglobulin gamma Fc region receptor III-B
  • Fc fragment of IgG receptor IIIb
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
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Properties