CPRiL

Protein Name	tripartite motif-containing 21
Organism	Mus musculus
Gene ID	20821
Gene Symbol	Trim21
UniProt	Q3U7K7 (Q3U7K7_MOUSE), Q3UCL2 (Q3UCL2_MOUSE)
Relationships	Total Number of functionally related compound(s) : 35 Total Number of Articles : 26
Description	tripartite motif-containing 21
Gene Summary	Predicted to enable identical protein binding activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of viral transcription; and protein ubiquitination. Predicted to act upstream of or within several processes, including antiviral innate immune response; positive regulation of non-canonical NF-kappaB signal transduction; and stress granule assembly. Located in cytoplasm. Is expressed in central nervous system; genitourinary system; retina; and thymus primordium. Orthologous to human TRIM21 (tripartite motif containing 21). [provided by Alliance of Genome Resources, Jun 2025]
synonyms	E3 ubiquitin-protein ligase TRIM21 52 kDa Ro protein 52 kDa ribonucleoprotein autoantigen Ro/SS-A 52kD Ro/SSA autoantigen RING-type E3 ubiquitin transferase TRIM21 SS-A Sjogren syndrome antigen A1 ro(SS-A) sjoegren syndrome type A antigen tripartite motif protein 21 tripartite motif-containing protein 21 Ro52 Ssa1 Click to show/hide the synonyms
Properties