Protein Name peroxiredoxin 5
Organism Homo sapiens
Gene ID 25824
Gene Symbol


UniProt P30044 (PRDX5_HUMAN)
Relationships Total Number of functionally related compound(s) : 539
Total Number of Articles : 647

peroxiredoxin 5

Gene Summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]

  • peroxiredoxin-5, mitochondrial
  • Alu co-repressor 1
  • TPx type VI
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