| Protein Name | ryanodine receptor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 114207 |
| Gene Symbol | Ryr1 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
22
Total Number of Articles : 19 |
Description |
ryanodine receptor 1 |
| Gene Summary |
Enables ryanodine-sensitive calcium-release channel activity. Involved in release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; response to estradiol; and response to purine-containing compound. Located in sarcolemma; sarcoplasmic reticulum membrane; and terminal cisterna. Is extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in central core disease; malignant hyperthermia; and multiminicore disease. Orthologous to human RYR1 (ryanodine receptor 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |