Protein Name | mechanistic Target of rapamycin |
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Organism | Drosophila melanogaster |
Gene ID | 47396 |
Gene Symbol | mTor |
UniProt | Q9VK45 (TOR_DROME), H1ZYB5 (H1ZYB5_DROME), M9PFS0 (M9PFS0_DROME) |
Relationships |
Total Number of functionally related compound(s) :
54
Total Number of Articles : 73 |
Description |
mechanistic Target of rapamycin |
Gene Summary |
Enables chromatin DNA binding activity; protein kinase activity; and protein self-association. Involved in several processes, including negative regulation of cellular catabolic process; regulation of synapse organization; and transmembrane receptor protein tyrosine kinase signaling pathway. Located in cytoplasm. Part of TORC1 complex and TORC2 complex. Is expressed in adult head. Human ortholog(s) of this gene implicated in autosomal dominant polycystic kidney disease; kidney angiomyolipoma; lung disease (multiple); prostate cancer; and type 2 diabetes mellitus. Orthologous to human MTOR (mechanistic target of rapamycin kinase). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |