| Protein Name | matrix metallopeptidase 8 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 63849 |
| Gene Symbol | Mmp8 |
| UniProt | O88766 (MMP8_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
52
Total Number of Articles : 44 |
Description |
matrix metallopeptidase 8 |
| Gene Summary |
Enables metal ion binding activity and peptidase activity. Involved in several processes, including cellular response to lipopolysaccharide; positive regulation of neuroinflammatory response; and positive regulation of tumor necrosis factor production. Located in extracellular space. Biomarker of brain infarction and congestive heart failure. Human ortholog(s) of this gene implicated in breast cancer and carotid artery disease. Orthologous to human MMP8 (matrix metallopeptidase 8). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |