Protein Name nuclear receptor subfamily 1, group I, member 2
Organism Rattus norvegicus
Gene ID 84385
Gene Symbol

Nr1i2

UniProt Q9R1A7 (NR1I2_RAT)
Relationships Total Number of functionally related compound(s) : 132
Total Number of Articles : 130
Description

nuclear receptor subfamily 1, group I, member 2

Gene Summary

Enables nuclear receptor activity. Predicted to be involved in several processes, including cellular response to molecule of bacterial origin; cellular response to type I interferon; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gene expression; negative regulation of DNA-templated transcription; and positive regulation of gene expression. Predicted to be located in intermediate filament cytoskeleton and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Biomarker of cholestasis and epilepsy. Orthologous to human NR1I2 (nuclear receptor subfamily 1 group I member 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • nuclear receptor subfamily 1 group I member 2
  • nuclear receptor subfamily 1, group 1, member 2
  • orphan nuclear receptor PXR
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Properties