| Protein Name | transketolase like 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 8277 |
| Gene Symbol | TKTL1 |
| UniProt | P51854 (TKTL1_HUMAN), B7Z7I0 (B7Z7I0_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 55 |
Description |
transketolase like 1 |
| Gene Summary |
The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
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