Protein Name ADAM metallopeptidase domain 9
Organism Homo sapiens
Gene ID 8754
Gene Symbol

ADAM9

UniProt Q13443 (ADAM9_HUMAN)
Relationships Total Number of functionally related compound(s) : 48
Total Number of Articles : 52
Description

ADAM metallopeptidase domain 9

Gene Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]

synonyms
  • disintegrin and metalloproteinase domain-containing protein 9
  • ADAM metallopeptidase domain 9 (meltrin gamma)
  • cellular disintegrin-related protein
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Properties