Protein Name BCL2 interacting protein 3
Organism Homo sapiens
Gene ID 664
Gene Symbol

BNIP3

UniProt Q12983 (BNIP3_HUMAN), Q6NVY4 (Q6NVY4_HUMAN)
Relationships Total Number of functionally related compound(s) : 184
Total Number of Articles : 225
Description

BCL2 interacting protein 3

Gene Summary

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014]

synonyms
  • BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
  • BCL2/adenovirus E1B 19kDa interacting protein 3
  • BCL2/adenovirus E1B interacting protein 3
Click to show/hide the synonyms
Properties