Protein Name | BCL2 interacting protein 3 |
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Organism | Homo sapiens |
Gene ID | 664 |
Gene Symbol | BNIP3 |
UniProt | Q12983 (BNIP3_HUMAN), Q6NVY4 (Q6NVY4_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
184
Total Number of Articles : 225 |
Description |
BCL2 interacting protein 3 |
Gene Summary |
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014] |
synonyms |
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Properties | |