Protein Name porcupine O-acyltransferase
Organism Homo sapiens
Gene ID 64840
Gene Symbol

PORCN

UniProt Q9H237 (PORCN_HUMAN)
Relationships Total Number of functionally related compound(s) : 47
Total Number of Articles : 27
Description

porcupine O-acyltransferase

Gene Summary

This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Aug 2013]

synonyms
  • protein-serine O-palmitoleoyltransferase porcupine
  • porcupine homolog
  • probable protein-cysteine N-palmitoyltransferase porcupine
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Properties