Protein Name transcobalamin 2
Organism Homo sapiens
Gene ID 6948
Gene Symbol

TCN2

UniProt P20062 (TCO2_HUMAN)
Relationships Total Number of functionally related compound(s) : 185
Total Number of Articles : 238
Description

transcobalamin 2

Gene Summary

This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

synonyms
  • transcobalamin-2
  • macrocytic anemia
  • transcobalamin II
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Properties