| Protein Name | glial fibrillary acidic protein |
|---|---|
| Organism | Mus musculus |
| Gene ID | 14580 |
| Gene Symbol | Gfap |
| UniProt | P03995 (GFAP_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
467
Total Number of Articles : 652 |
Description |
glial fibrillary acidic protein |
| Gene Summary |
A structural constituent of cytoskeleton. Involved in regulation of chaperone-mediated autophagy. Acts upstream of or within with a positive effect on D-aspartate import across plasma membrane; gene expression; and intracellular protein transport. Acts upstream of or within several processes, including long-term synaptic potentiation; neurogenesis; and positive regulation of Schwann cell proliferation. Located in several cellular components, including astrocyte end-foot; cell body; and intermediate filament. Is expressed in several structures, including alimentary system; hemolymphoid system; integumental system; nervous system; and sensory organ. Used to study Alexander disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein). [provided by Alliance of Genome Resources, Jun 2025] |
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