Protein Name glial fibrillary acidic protein
Organism Mus musculus
Gene ID 14580
Gene Symbol


UniProt P03995 (GFAP_MOUSE)
Relationships Total Number of functionally related compound(s) : 467
Total Number of Articles : 652

glial fibrillary acidic protein

Gene Summary

A structural constituent of cytoskeleton. Involved in regulation of chaperone-mediated autophagy. Acts upstream of or within with a positive effect on D-aspartate import across plasma membrane; gene expression; and intracellular protein transport. Acts upstream of or within several processes, including intermediate filament organization; long-term synaptic potentiation; and neurogenesis. Located in several cellular components, including astrocyte end-foot; cell body; and intermediate filament. Is expressed in several structures, including alimentary system; hemolymphoid system; integumental system; nervous system; and sensory organ. Used to study Alexander disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein). [provided by Alliance of Genome Resources, Apr 2022]

  • glial fibrillary acidic protein
  • intermediate filament protein
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