Protein Name histone deacetylase 4
Organism Rattus norvegicus
Gene ID 363287
Gene Symbol

Hdac4

UniProt Q99P99 (HDAC4_RAT)
Relationships Total Number of functionally related compound(s) : 48
Total Number of Articles : 44
Description

histone deacetylase 4

Gene Summary

Enables promoter-specific chromatin binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to parathyroid hormone stimulus; and positive regulation of lamellipodium assembly. Located in A band and Z disc. Part of protein-containing complex. Biomarker of fetal alcohol spectrum disorder and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in ataxia telangiectasia; eating disorder; and retinal degeneration. Orthologous to human HDAC4 (histone deacetylase 4). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • histone deacetylase 4
  • HD4
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Properties