| Protein Name | C-C motif chemokine receptor 6 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1235 |
| Gene Symbol | CCR6 |
| UniProt | P51684 (CCR6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
93
Total Number of Articles : 92 |
Description |
C-C motif chemokine receptor 6 |
| Gene Summary |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
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