Protein Name thymocyte selection associated
Organism Homo sapiens
Gene ID 387357
Gene Symbol

THEMIS

UniProt Q8N1K5 (THMS1_HUMAN)
Relationships Total Number of functionally related compound(s) : 11
Total Number of Articles : 17
Description

thymocyte selection associated

Gene Summary

This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

synonyms
  • protein THEMIS
  • GRB2-associated protein
  • signaling phosphoprotein specific for T cells
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Properties