Protein Name nucleobindin 2
Organism Rattus norvegicus
Gene ID 59295
Gene Symbol

Nucb2

UniProt Q9JI85 (NUCB2_RAT), G3V8R1 (G3V8R1_RAT)
Relationships Total Number of functionally related compound(s) : 109
Total Number of Articles : 91
Description

nucleobindin 2

Gene Summary

Enables G-protein alpha-subunit binding activity; guanyl-nucleotide exchange factor activity; and tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of cell communication; positive regulation of testosterone secretion; and response to melanocyte-stimulating hormone. Located in Golgi medial cisterna and extracellular space. Biomarker of alcohol dependence; obesity; and type 2 diabetes mellitus. Orthologous to human NUCB2 (nucleobindin 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • nucleobindin-2
  • DNA-binding protein NEFA
  • nesfatin-1
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Properties