Protein Name Rho guanine nucleotide exchange factor 4
Organism Homo sapiens
Gene ID 50649
Gene Symbol

ARHGEF4

UniProt Q9NR80 (ARHG4_HUMAN), Q9NTG0 (Q9NTG0_HUMAN)
Relationships Total Number of functionally related compound(s) : 33
Total Number of Articles : 21
Description

Rho guanine nucleotide exchange factor 4

Gene Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by this gene may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jun 2013]

synonyms
  • rho guanine nucleotide exchange factor 4
  • APC-stimulated guanine nucleotide exchange factor 1
  • Rho guanine nucleotide exchange factor (GEF) 4
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Properties