| Protein Name | cryptochrome circadian regulator 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12952 |
| Gene Symbol | Cry1 |
| UniProt | P97784 (CRY1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
48
Total Number of Articles : 64 |
Description |
cryptochrome circadian regulator 1 |
| Gene Summary |
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of this gene results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Feb 2014] |
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