Protein Name Zic family member 1
Organism Homo sapiens
Gene ID 7545
Gene Symbol

ZIC1

UniProt Q15915 (ZIC1_HUMAN)
Relationships Total Number of functionally related compound(s) : 55
Total Number of Articles : 39
Description

Zic family member 1

Gene Summary

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008]

synonyms
  • zinc finger protein ZIC 1
  • Zic family member 1 (odd-paired homolog, Drosophila)
  • Zinc finger protein of the cerebellum 1
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Properties