Protein Name glutamate ionotropic receptor kainate type subunit 1
Organism Homo sapiens
Gene ID 2897
Gene Symbol

GRIK1

UniProt P39086 (GRIK1_HUMAN), E7ENK3 (E7ENK3_HUMAN), E7EPZ0 (E7EPZ0_HUMAN), E9PD61 (E9PD61_HUMAN), B7Z256 (B7Z256_HUMAN), B7Z3V7 (B7Z3V7_HUMAN), E7EPY9 (E7EPY9_HUMAN)
Relationships Total Number of functionally related compound(s) : 120
Total Number of Articles : 132
Description

glutamate ionotropic receptor kainate type subunit 1

Gene Summary

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • glutamate receptor ionotropic, kainate 1
  • GluK1(del_e2)
  • excitatory amino acid receptor 3
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Properties