| Protein Name | dual oxidase |
|---|---|
| Organism | Danio rerio |
| Gene ID | 565097 |
| Gene Symbol | duox |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
7
Total Number of Articles : 10 |
Description |
dual oxidase |
| Gene Summary |
Predicted to enable superoxide-generating NAD(P)H oxidase activity. Acts upstream of or within several processes, including hydrogen peroxide biosynthetic process; leukocyte migration; and thyroid gland development. Predicted to be located in apical plasma membrane. Predicted to be integral component of membrane. Predicted to be part of NADPH oxidase complex. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; endocrine system; epidermis; eye; and pleuroperitoneal region. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in congenital hypothyroidism and thyroid dyshormonogenesis 6. Orthologous to human DUOX1 (dual oxidase 1) and DUOX2 (dual oxidase 2). [provided by Alliance of Genome Resources, Apr 2022] |
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