Protein Name translocator protein
Organism Homo sapiens
Gene ID 706
Gene Symbol


UniProt P30536 (TSPO_HUMAN), O76068 (O76068_HUMAN)
Relationships Total Number of functionally related compound(s) : 697
Total Number of Articles : 869

translocator protein

Gene Summary

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]

  • translocator protein
  • benzodiazepine peripheral binding site
  • mitochondrial benzodiazepine receptor
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