| Protein Name | SET domain containing 1A, histone lysine methyltransferase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 9739 |
| Gene Symbol | SETD1A |
| UniProt | O15047 (SET1A_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
72
Total Number of Articles : 94 |
Description |
SET domain containing 1A, histone lysine methyltransferase |
| Gene Summary |
The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily. [provided by RefSeq, Dec 2016] |
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