Protein Name paraoxonase 1
Organism Rattus norvegicus
Gene ID 84024
Gene Symbol

Pon1

UniProt P55159 (PON1_RAT)
Relationships Total Number of functionally related compound(s) : 172
Total Number of Articles : 126
Description

paraoxonase 1

Gene Summary

Enables aryldialkylphosphatase activity. Involved in several processes, including response to fatty acid; response to fluoride; and response to lipopolysaccharide. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and hematologic cancer (multiple). Orthologous to human PON1 (paraoxonase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • serum paraoxonase/arylesterase 1
  • A-esterase 1
  • PON 1
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Properties